Disease Prevention Science Course Research
Mastering lipid analysis Kobayashi Laboratory
1. Bioactive lipid metabolism and function
2. Lipid metabolome analysis with a foundation of lipid analysis
3. The influence of essential fatty acids on biological function (lipid nutrition science)
Q: What kinds of research are you actually doing?
Our laboratory comprehensively analyzes lipid metabolism using animal models for human diseases. (The comprehensive analysis of metabolism is referred to as metabolomics.) Through the vehicle of metabolomics, our students research the causation and prevention of disease.
Q: What specific things can students learn in your laboratory?
It is possible to obtain an extremely large volume of data from the analysis of pathological animal models. By comprehensively analyzing and taking an overall view of that data, we are able to meaningful changes even when the changes are small. Knowhow for discovering research topics in a large volume of data is applicable to a variety of scientific fields. Students also become able to perform general biochemistry and molecular biology experiments. In addition, through their research work, students naturally acquire problem solving skills, research design skills, and the ability to communicate information to others in an easy-to-understand manner.
Q: In what kinds of fields are students who have studied in your laboratory active?
We have many graduates who are working at companies using the techniques that they learned in graduate school. The fields involved are centered in pharmaceutical, food, and analysis related areas. For example, our graduates are active in roles such as that of analysis expert in the research facilities of companies like Astellas Pharma, Otsuka Pharmaceutical, Fancl, Mitsubishi Chemical Medience (now called LSI Medience), Lotte, Kirin Beer, and Asahi Beer. This includes graduates who are working as lawyers in company intellectual property departments and graduates who are in companies as science communicators. Of course, we also have graduates who are active working as educators in universities as well as junior high and high schools.
Q: Are graduate students who are working adults able to study here?
There is a case where a person working in a food company utilized his company’s research in the preparation of his dissertation in my laboratory. Working at his company during the week and immersed in his own research in the evening and on weekends, he was able to acquire a doctorate on the same schedule as a normal doctoral course.
Q: Location of your lab?
The research performed at Ochanomizu University is centered on lipid metabolomics analysis and biochemistry experiments. The animal experimentation using disease models is performed at research institute (Tokyo Metropolitan Institute of Medical Science, etc.) outside the university. It varies by topic, but many students gain experience at multiple laboratories while doing research at the university and at research institutes.
Q: What is your opinion of the Disease Prevention Science Course lectures?
In addition to an overview of disease prevention science, this course covers the special topic of data science in order to deepen student understanding with respect to data handling. We believe that the course content will prove useful both in the research done for other lecture subjects and in the building of the student’s future career.
Q: Please say a word to students who want to enroll.
The metabolomics-based comprehensive analysis method is a basic methodology that can also be utilized in other fields. I want our students to actively take on the challenges presented by this field and to be widely active in society as a Ph.D.
For details concerning this laboratory see here
Kobayashi Laboratory, Ochanomizu University